Exocrine Pancreatic Insufficiency (EPI) is treated with pancreatic enzyme replacement therapy (PERT). This involves taking pancreatic enzyme supplements with meals to aid digestion. These enzymes help break down fats, proteins, and carbohydrates, improving nutrient absorption. Dosage varies based on individual needs, and adjustments are made over time. Patients may also be advised to follow a low-fat diet and take vitamins (A, D, E, K) to address malabsorption. In some cases, additional treatments like acid-reducing medications or insulin therapy for associated diabetes may be necessary. Regular follow-ups with a healthcare provider are crucial for monitoring progress.